采用表面改性法制备了Ｖ２Ｏ５ＳｉＯ２ ， ＭｏＯ３ＳｉＯ２ ， Ｖ２Ｏ５ＭｏＯ３ＳｉＯ２ 复合氧化物催化剂，并用ＴＰＲ和ＩＲ 技术研究了催化剂的表面结构及Ｖ Ｏ ， Ｍｏ Ｏ 的活性，同时用化学吸附ＩＲ 技术研究了催化剂样品对异丁烷的化学吸附性能． 实验结果表明： 这些复合氧化物催化剂对异丁烷都有较高的化学吸附能力；ＳｉＯ２ 能缓解表面Ｌｅｗｉｓ 碱位Ｖ Ｏ 和 Ｍｏ Ｏ 的氧化能力，有利于选择氧化． V2O5SiO2, MoO3SiO2, V2O5MoO3SiO2 composite oxide catalysts were prepared by surface modification method. The surface structure and V O, Mo O activity of the catalysts were investigated by TPR and IR techniques. At the same time, the chemical adsorption IR Technical study of the catalyst sample of isobutane chemisorption performance. The experimental results show that these composite oxide catalysts have high chemisorption ability for isobutane. SiO2 can alleviate the oxidation ability of surface Lewis base V O and Mo O, which is good for selective oxidation.