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目的探讨早期营养支持对食管癌患者术后恢复及免疫指标的影响。方法选取2014年10月—2016年8月在安阳肿瘤医院接受治疗的69例食管癌患者,依据建档顺序分组,对照组34例予以肠外营养支持,观察组35例予以肠内与肠外联合营养支持,观察比较两组首次排便、排气及出院时间,并统计两组各免疫指标[免疫球蛋白A(IgA)、IgG、IgM]水平变化情况及并发症发生率。结果观察组首次排气、排便及出院时间均小于对照组,差异具有统计学意义(P<0.05);术后1周观察组IgG及IgM水平均高于对照组,差异具有统计学意义(P<0.05);观察组并发症发生率为11.43%(4/35),对照组为8.82%(3/34),组间比较差异无统计学意义(P>0.05)。结论早期营养支持可改善食管癌患者术后免疫功能,促进术后恢复,且安全性高。
Objective To investigate the effect of early nutritional support on postoperative recovery and immune parameters in patients with esophageal cancer. Methods A total of 69 patients with esophageal cancer treated at Anyang Cancer Hospital from October 2014 to August 2016 were selected according to the order of filing, 34 patients in the control group were given parenteral nutrition support, and 35 patients in the observation group were given enteral and parenteral Combined nutritional support, the first defecation, excretion and discharge time were observed and compared between the two groups. The changes of the immune indexes [immunoglobulin A (IgA), IgG, IgM] and the incidence of complications were compared between the two groups. Results The first discharge, defecation and discharge time in the observation group were all less than those in the control group (P <0.05), and the levels of IgG and IgM in the observation group were significantly higher than those in the control group <0.05). The complication rate in the observation group was 11.43% (4/35), while that in the control group was 8.82% (3/34). There was no significant difference between the two groups (P> 0.05). Conclusion Early nutritional support can improve postoperative immune function, promote postoperative recovery and safety of patients with esophageal cancer.