This paper elaborates the chemical constituent change principles of deep geothermal fluid during the process of upward movement. It summarizes research methods of hydrochemistry, isotope and numerical modelling technique for the physiochemical processes such as decreasing temperature, shallow groundwater infusion, and degassing. The multi-component chemical geothermometry methods including gas geochemical method are discussed. High-temperature geothermal fields in China are mostly located in the southwest with frequent new tectonic movements, especially in Tibet high-temperature geothermal areas. Therefore the paper also focuses the status of high-temperature geothermal fluid research. At last, it’s pointed out in the paper that in the future we can start from typical high-temperature geothermal zones and geothermal fields to explore optimization of the multi-component geothermometry method and use it in the reconstruction and analogue of the formation mechanism and internal relevancy of regional geothermal systems. This paper elaborates the chemical constituent change principles of deep geothermal fluid during the process of upward movement. It summarizes research methods of hydrochemistry, isotope and numerical modeling techniques for the physiochemical processes such as decreasing temperature, shallow groundwater infusion, and degassing. The multi- component chemical geothermometry methods including gas geochemical methods are discussed. High-temperature geothermal fields in China are mostly located in the southwest with frequent new tectonic movements, especially in Tibet high-temperature geothermal areas. Therefore the paper also focuses on the status of high-temperature At last, it’s pointed out in the paper that in the future we can start from typical high-temperature geothermal zones and geothermal fields to explore optimization of the multi-component geothermometry method and use it in the reconstruction and analogue of the formation mechanism and internal relevancy of regional geothermal systems.