论文部分内容阅读
背景:糖尿病患者冠状动脉病变的危险性是当前临床研究的热点问题。目的:应用电子束CT(EBT)心脏扫描,了解2型糖尿病患者冠状动脉病变的发生情况,分析2型糖尿病患者冠状动脉病变发生的危险性。设计:以伴冠状动脉病变的2型糖尿病患者为研究对象,观察对比研究。单位:一所军医大学医院的老年病科病房。对象:收集2002-01/2004-06第四军医大学西京医院老年病科经EBT扫描的住院患者共93例,男80例,女13例,年龄36～78岁。其中25例健康查体者作为正常血糖对照组,男22例,女3例;其余按病情分为血糖异常组和冠心病组。血糖异常组57例,男49例,女8例,包括糖耐量低减组(IGT)29例,糖尿病组28例,44例患者伴有不同程度的心脏症状;冠心病组11例,男9例,女2例。纳入标准:2型糖尿病患者符合1979年美国糖尿病协会的诊断标准,冠心病患者符合1979年国际心脏联合专题组冠心病诊断标准并经冠状动脉造影检查确诊。排除标准:①1型糖尿病患者;②患重大躯体疾病者。方法:93例受试者行心脏EBT平扫及增强扫描,计算冠状动脉钙化发生率、钙化积分、冠状动脉狭窄支数和软斑数,同时收集血糖、糖化血红蛋白(HbA1c)、血脂等相关信息,进行冠状动脉的组间比较和危险性分析。主要观察指标:各组冠状动脉钙化发生率、冠状动脉狭窄支数和软斑数的比较,冠
BACKGROUND: The risk of coronary artery disease in diabetic patients is a hot issue in current clinical research. OBJECTIVE: To study the incidence of coronary lesions in type 2 diabetic patients by e-beam CT (EBT) cardiac scan and analyze the risk of coronary lesions in type 2 diabetic patients. Design: Patients with type 2 diabetes mellitus with coronary artery disease were studied and compared. Unit: Geriatric Unit Ward at a Military Medical University Hospital. PARTICIPANTS: A total of 93 hospitalized patients with EBT scans were enrolled in the Department of Geriatrics, Xijing Hospital, Fourth Military Medical University from January 2002 to June 2004, including 80 males and 13 females, aged 36-78 years. Among them, 25 cases of healthy people as normal blood glucose control group, 22 males and 3 females; the rest according to the disease is divided into abnormal blood glucose group and coronary heart disease group. 57 cases of abnormal blood glucose, 49 males and 8 females, including impaired glucose tolerance group (IGT) in 29 cases, 28 cases of diabetic patients, 44 patients with varying degrees of cardiac symptoms; coronary heart disease group of 11 patients, male 9 Cases, female 2 cases. Inclusion criteria: Patients with type 2 diabetes mellitus met the diagnostic criteria of the American Diabetes Association in 1979, and patients with coronary heart disease were diagnosed with CHD according to the 1979 International Symposium on Cardiac Artery and confirmed by coronary angiography. Exclusion criteria: ① type 1 diabetes; ② major body diseases. Methods: Ninety-three subjects underwent echocardiography and enhanced scan of the heart to calculate the incidence of coronary calcification, calcification score, the number of coronary artery stenosis and soft spots. Meanwhile, the related information such as blood glucose, HbA1c, Coronary intergroup comparisons and risk analyzes were performed. MAIN OUTCOME MEASURES: The incidence of coronary artery calcification, the number of coronary stenosis and soft spots in each group, the crown