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患者男,17岁。同种异基因造血干细胞骨髓移植术后1年零7个月,双手背、面部及双肘伸侧出现皮疹,活动受限1个月。患者2年前患急性B淋巴细胞白血病,1年零7个月前接受非血缘造血干细胞移植,供者为男性。术后口服环孢素及泼尼松7个月,停药后出现口腔、眼睛、皮肤及肝脏轻度排异,白细胞分类中嗜酸性粒细胞0.15。再次口服环孢素50 mg/d及泼
Patient male, 17 years old. Allogeneic hematopoietic stem cell transplantation after bone marrow transplantation 1 year and 7 months, both hands back, facial and elbow stretch side of the rash, limited activity for 1 month. The patient developed acute B-lymphoblastic leukemia two years ago and received non-blood-derived hematopoietic stem cell transplantation one year and seven months prior to delivery for a male. After oral administration of cyclosporine and prednisone for 7 months, there was mild rejection of oral cavity, eyes, skin and liver after drug withdrawal, and eosinophil 0.15 in leukocyte classification. Again oral cyclosporine 50 mg / d and splash