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超生理剂量的糖皮质激素(Glue oc-ortleoids GC),具有显著抗炎、抗毒、抗免疫和抗休克作用。这四大抗作用早已广泛用于临床许多疾病,且为抢救某些重危病人所必需,但对其抗炎作用原理至今尚未完全阐明,现就目前对 GC 抗炎作用原理的认识综述如下。炎症是机体对各种致病因素损害刺激所产生的一种防御性反应。炎症的临床表现虽有许多不同,但无论何种原因何种组织的炎症,其基本病理变化都包括变质、渗出和增生三项过程。炎症反应过于强烈则对机体有害,此时需抗炎治疗。GC 的抗炎作用强度名列各类抗炎作用药物之
Super physiological dose of glucocorticoids (Glue oc-ortleoids GC), with significant anti-inflammatory, anti-toxic, anti-immune and anti-shock effect. The four major anti-role has long been widely used in clinical many diseases, and is necessary for the rescue of some critically ill patients, but its anti-inflammatory effect has not been fully elucidated so far, now the understanding of the principle of GC anti-inflammatory effect are summarized below. Inflammation is a defensive reaction of the body to a variety of pathogenic factors that impair the stimulation. Although there are many different clinical manifestations of inflammation, but no matter what kind of tissue inflammation, the basic pathological changes include deterioration, exudation and proliferation of the three processes. Inflammatory reaction is too strong is harmful to the body, this time need anti-inflammatory treatment. The anti-inflammatory effect of GC is ranked among the various anti-inflammatory drugs