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日前认为急性心肌梗死(AMI)时神经激素的活化水平不仅能反映血流动力学的代偿程度,并可加速心衰的发生和增加并发严重室性心律失常的危险性。因此,对AMI时的神经激素水平进行测评将有助于AMI预后的客观评价。方法研究对象为145例AMI患者(男105例,女40例,均龄68±10岁)。除常规接受溶栓剂、β-阻滞剂、利尿剂与硝酸甘油外,并随机接受依那普利或安慰剂。于AMI 3天后分测各患者的血浆
Recently, it was thought that the activation of neurohormones in acute myocardial infarction (AMI) not only reflects hemodynamic compensatory degree, but also accelerates the occurrence of heart failure and increases the risk of severe ventricular arrhythmias. Therefore, the assessment of neurohormones at AMI will contribute to the objective evaluation of the prognosis of AMI. Methods The subjects were 145 AMI patients (105 males and 40 females, mean age 68 ± 10 years). In addition to conventional thrombolytic agents, beta-blockers, diuretics and nitroglycerin, randomized to enalapril or placebo. Each patient’s plasma was measured 3 days after AMI