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目的探讨支原体肺炎患儿的T淋巴细胞变化及与支气管哮喘的关系。方法支原体肺炎26例,支气管哮喘32例,正常对照组34例;用同位素放免法检测血清总IgE水平,微量玻片法观察T淋巴细胞起化性。结果支原体肺炎组T淋巴细胞趋化值为(5.03士0.24%);总IgE629.74士172.85mg/L,明显高于正常对照组的(0.48土0.04)%和201.50土48.26mg/L,接近于支气管哮喘组的(8.27土0.42)%和754.82士197.88mg/L。结论支原体肺炎与支气管哮喘类同,存在明显的免疫功能紊乱。支原休感染与支气管哮喘之间存在密切关系。
Objective To investigate the changes of T lymphocyte in children with Mycoplasma pneumonia and its relationship with bronchial asthma. Methods Mycoplasma pneumonia was observed in 26 cases, bronchial asthma in 32 cases and normal control group in 34 cases. Serum total IgE levels were measured by isotope radioimmunoassay and T lymphocyte activation was observed by micro-slide method. Results The chemotactic value of T lymphocyte in mycoplasma pneumonia group was (5.03 ± 0.24%), the total IgE was 62.74 ± 172.85 mg / L, which was significantly higher than that in the control group (0.48 ± 0.04%), And 48.26 mg / L at 201.50, which was close to (8.27 ± 0.42)% and 754.82 ± 197.88 mg / L in the bronchial asthma group. Conclusion Mycoplasma pneumonia and bronchial asthma are the same, there is a clear immune dysfunction. Mycoplasma infection and bronchial asthma are closely related.