目的探讨重症急性胰腺炎的诊断及治疗。方法回顾性分析2001-01-2009-01在洛阳市第三人民医院收治的38例重症急性胰腺炎的诊断及治疗。结果内科综合治疗25例,内镜下Oddi括约肌切开引流治疗8例,外科手术5例,死亡8例,病死率21%(8/38),治愈率79%(30/38)。结论重症胰腺炎病情危重、表现复杂,早期诊断并采取正确的治疗措施,对其预后至关重要。 Objective To investigate the diagnosis and treatment of severe acute pancreatitis. Methods The diagnosis and treatment of 38 cases of severe acute pancreatitis admitted to the Third People ’s Hospital of Luoyang from January 2001 to January 2009 were retrospectively analyzed. Results Twenty-five patients were treated by internal medicine combined with Oddi sphincter excision and drainage in 8 cases. Surgical operation was performed in 5 cases and in 8 cases, the mortality rate was 21% (8/38). The cure rate was 79% (30/38). Conclusions Severe pancreatitis is critically ill and complicated. Early diagnosis and correct treatment are of crucial importance to its prognosis.