临床上肾脏疾病中并不存在所谓肾纤维症的疾病概念。这里所谓肾纤维症是指因各种原因肾间质结缔组织纤维增生。导致肾间质纤维增生的疾病有因肾血管或原发性肾小球损害引起的继发性肾间质纤堆增生和由于微生物、药物、重金属、免疫性疾病、代谢病、阻塞性尿路疾患、恶性肿瘤、遗传病等引起的原发性肾间质纤维增生两种情况。本文就该症的病因、纤维化机制、诊断和治疗加以叙述。一、肾血管或原发性肾小球损害引起的继发性间质纤维增生已知导致肾血管损害的疾病有良性及恶性肾硬化症、肾血管性高血压、肾梗塞、肾静脉血栓症等。每一疾病都有其特征性的病理组织学所见。但他们共同的特点是肾间质纤维增生。其发生机制一般认为是由 There is no concept of disease called renal fibrosis in clinical kidney disease. The so-called renal fibrosis refers to renal interstitial connective tissue fibrosis for a variety of reasons. The diseases that cause renal interstitial fibrosis include secondary renal interstitial fibrosis caused by renal blood vessel or primary glomerular damage, and diseases due to microorganisms, drugs, heavy metals, autoimmune diseases, metabolic diseases, obstructive urinary tract Disease, cancer, genetic disease caused by two cases of primary renal interstitial fibrosis. This article describes the etiology of the disease, fibrosis mechanisms, diagnosis and treatment. First, renal vascular or primary glomerular damage secondary interstitial fibrosis known to cause renal vascular damage of the disease with benign and malignant nephrosclerosis, renal vascular hypertension, renal infarction, renal vein thrombosis Wait. Each disease has its own characteristic histopathology. But their common feature is renal interstitial fibrosis. Its mechanism is generally considered to be