急性肾功能衰竭(acute renal failure,ARF)是一种常见的临床危急重症,以泌尿功能急剧障碍和继发的水、电解质平衡紊乱内环境稳态调节失衡为特征,死亡率在50%以上,甚至高达80%[1]。血管和肾小管是ARF发生的主要因素[2],如急性肾小管上皮细胞坏死致小管液回漏可使ARF发生。但由于 Acute renal failure (ARF) is a common clinical critically ill characterized by an imbalance of homeostatic regulation of acute urinary dysfunction and secondary water and electrolyte balance disorders with a mortality rate of over 50% Even up to 80% [1]. Blood vessels and tubules are the main causes of ARF [2], such as acute tubular epithelial cell necrosis caused by tubule leakage can make ARF. But thanks