间质性肺病(ILD)是以肺泡壁为主要病变所引起的一组疾病。这里所指的间质,除肺泡间质本身外,还包含肺泡上皮细胞、血管内皮细胞等的实质。它的病变不仅限于肺泡壁,也可波及细支气管领域。由于细支气管领域和肺泡壁纤维化使肺的顺应性降低,导致肺容量减少和限制性通气障碍。 Interstitial lung disease (ILD) is a group of diseases caused by the alveolar wall as the main lesion. The stroma referred to here, in addition to the alveolar interstitium itself, also contains the essence of alveolar epithelial cells, vascular endothelial cells. Its disease is not limited to the alveolar wall, but also spread to the area of ​​bronchioles. Reduced lung compliance due to bronchioles and alveolar wall fibrosis leads to reduced lung capacity and restrictive ventilatory disorders.