芥子气是一种双功能烃化剂，易与细胞内ＤＮＡ、ＲＮＡ和蛋白质等大分子物质起烃化反应，中毒后可以引起机体组织细胞的损伤以至死亡。细胞死亡方式有凋亡和坏死两种，但芥子气引起细胞坏死方式国内外还很少报道。小肠粘膜分裂旺盛的上皮细胞对芥子气较为敏感，致死剂量芥子气 Mustard gas is a bifunctional alkylating agent that easily alkalizes with macromolecular substances such as DNA, RNA and protein in cells. After being poisoned, it can cause cell damage and even death. There are two ways of cell death: apoptosis and necrosis, but the way of mustard cell death caused by cell death is rarely reported at home and abroad. Small intestinal mucosa exudes epithelial cells are more sensitive to mustard, lethal dose mustard