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OKT3 ( murine monoclonal antibody CD3;muromonab- CD3)是抑制肾移植排异反应的重要药物 ,但临床应用中发现 ,该药能引起可逆性感音神经性聋。该文对 OKT3致聋的发生率及停药后耳聋的恢复情况进行前瞻性研究。 1996年 7月～ 1997年 7月 ,有 7例肾移植患者接受 OKT3进行免疫抑
OKT3 (murineab-CD3) is an important drug that inhibits renal transplant rejection, but it has been found in clinical application that it can cause reversible sensorineural hearing loss. The article prospectively studied the incidence of deafness and recovery of deafness after withdrawal from OKT3. From July 1996 to July 1997, 7 patients undergoing renal transplantation received OKT3 for immunosuppression