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从豆科的决明子(Cassia tora L.)种子中分到一种新的萘酚-α-吡喃酮衍生物toralactone是一种淡黄色针状或柱状结晶,无味、无嗅、可升华、无旋光性。其氯仿溶液在紫外线下呈现蓝紫色强萤光。结晶在日光下渐变为黄褐色,微溶于甲醇、苯和乙酸乙酯,溶于氯仿,并在Mg(OAC)_2-乙醇液及浓硫酸中溶解呈淡蓝色。氯化铁及Gibbs反应均呈阳性。决明子1公斤原料用甲醇提取,在浓缩的提取液中加入10%硫酸,滤取沉淀,通过硅胶柱层析,纯化后得150毫克toralactone纯品,熔点253～254℃。元素分析及质谱结果确定其分子式为C_(15)H_(12)O_5,经红外光谱和核磁共振谱测定,最后证明toralactone的结构式为(Ⅰ):
A new naphthol-α-pyranone derivative, toralactone, is a pale yellow acicular or columnar crystal that is odorless, odorless, sublimated, and sublimated, from the seeds of Cassia tora L. Optical rotation. Its chloroform solution shows strong blue-violet fluorescence under ultraviolet light. Crystallization in the sunlight gradient to brown, slightly soluble in methanol, benzene and ethyl acetate, soluble in chloroform, and Mg (OAC) _2-ethanol solution and concentrated sulfuric acid dissolved in pale blue. Ferric chloride and Gibbs reaction were positive. Cassia 1 kg of raw materials extracted with methanol, the concentrated extract was added 10% sulfuric acid, the precipitate was filtered off and purified by silica gel column chromatography to give 150 mg toralactone pure product, mp 253-254 ° C. Elemental analysis and mass spectrometry confirmed that the molecular formula was C_ (15) H_ (12) O_5. The results of IR and 1HNMR indicated that the structural formula of toralactone was (Ⅰ):