作者于1986年5月～1987年6月在莫桑比克马普托中心医院用阿莫地喹加磺胺多辛-乙胺嘧啶以及磺胺多辛-乙胺嘧啶治疗10岁以上的抗氯喹恶性疟患者59例。疟原虫抗性采用WHO体内法测定。组Ⅰ治疗30例,以阿莫地喹25～30mg/kg(基质)3天分服(10,10,5mg/kg),第3天加服磺胺多辛26～30mg/kg与乙胺嘧啶1.25～1.5mg/kg。组Ⅱ治疗29例,第1天服用磺胺多辛25～ The authors treated amiodaropramine-pyrimethamine and sulfadoxine-pyrimethamine in the Maputo Central Hospital in Mozambique between May 1986 and June 1987 for anti-chloroquine-resistant malaria patients over the age of 10 59 example. Plasmodium resistance was determined by the WHO in vivo method. Group Ⅰ treatment of 30 cases, amodiaquine 25 ~ 30mg / kg (matrix) 3 days of service (10,10,5 mg / kg), on the 3rd day plus sulfadoxine 26 ~ 30mg / kg and pyrimethamine 1.25 ~ 1.5mg / kg. Group Ⅱ treatment in 29 cases, the first day of taking sulfadox 25 ~