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用改良Rosata方法造成家兔实验性腹腔淤血症。用显微电视录像反复再生静画步进法测量川芎嗪对淤血前后肠系膜10μm以下毛细血管血液动力学的影响。结果表明:川芎嗪可使血淤后毛细血管血流速度加快,血流量增多,开放毛细血管数增多;可抑制白细胞游出。
The modified Rosata method was used to induce experimental abdominal cavity disease in rabbits. The effect of tetramethylpyrazine on hemodynamics of mesenteric capillaries below 10 μm before and after congestion was measured by repetitively recreating still pictures using microscopic video recording. The results showed that: Ligustrazine can increase blood flow velocity after blood clotting, increase blood flow, increase the number of open capillaries, and inhibit leukocyte outflow.