目的报告2例患者在短时间内非职业性汞接触引起皮肤损害的情况。方法回顾性分析2例患者双手接触金属汞致变应性皮疹伴肝细胞损伤及双手异常发热的情况。结果 2例患者在接触汞2~4 d后出现了不同的皮肤损害,1例出现变应性皮肤病变,1例仅表现为双手异常发热。结论短时间内接触汞可引起急性中毒,也可导致机体的变态反应。应加强金属汞的管理,做好有关知识的宣传教育。 Objective To report two cases of skin damage caused by non-occupational mercury exposure in a short period of time. Methods Retrospective analysis of two cases of patients with both hands exposed to metal mercury allergic rash with liver cell injury and abnormal fever both hands. Results Two patients had different skin lesions after exposure to mercury for 2-4 days, one had allergic skin lesions, and one had only abnormal fever with both hands. Conclusions Exposure to mercury within a short period of time can cause acute poisoning and can also cause the body’s allergic reaction. The management of metal mercury should be strengthened so that publicity and education on knowledge can be carried out.