连续以电子显微镜研究登革2型病毒感染的白纹伊蚊,显示复制的病毒微粒及囊状结构局限在活的粗糙的内质网状组织细胞中。在病毒体的表面未发现细的颗粒,但在哺乳动物细胞产生的病毒体的表面上也没有发现小颗粒,而在病毒微粒包膜上则可见。在受染的小鼠神经元中没有发现核受累和细胞机能明显损伤的证据。真正的病毒复制是局限在唾液腺细胞及神经组织细胞,而在中肠、血细胞、表皮的细胞、脂肪体及前肠则较少。 Continuous examination of dengue virus type 2 infected Aedes albopictus with an electron microscope revealed that the replicative virus particles and vesicular structures were confined to viable, rough endoplasmic reticulum tissue cells. No fine particles were found on the surface of the virion, but no small particles were found on the surface of the virion produced by mammalian cells, but visible on the envelope of the viral particles. No evidence of nuclear involvement and significant impairment of cellular function was found in infected mouse neurons. True virus replication is confined to salivary gland cells and nerve tissue cells, while in the midgut, blood cells, epidermal cells, fat body and foregut is less.