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目的探讨图象细胞形态定量分析技术在上尿路移行细胞癌中的应用价值。方法应用图象细胞分析技术，对３５例肾盂、输尿管移行细胞癌组织进行检测、比较。结果肿瘤细胞核面积、周长、最小径，以及ＤＮＡ含量、指数、倍体等与肿瘤病理分级或临床分期呈正相关趋势；２年内膀胱肿瘤复发以及５年生存时间与肿瘤细胞核形态定量分析、ＤＮＡ含量等有密切关系。结论核形态定量分析、ＤＮＡ含量测定对上尿路移行细胞癌的诊断、恶性程度估计具有一定的参考价值，ＤＮＡ含量是影响预后的一个重要因素。
Objective To investigate the value of image cytometry in the diagnosis of upper urinary tract transitional cell carcinoma. Methods 35 cases of renal pelvis and ureter transitional cell carcinoma were detected and compared by image cytometry. Results The tumor cell nuclear area, perimeter, minimum diameter, DNA content, index, ploidy and so on were positively correlated with the pathological grade or clinical stage of tumor. The recurrence of bladder tumor and the 5-year survival time and the quantitative analysis of tumor cell nuclear morphology, DNA content There is a close relationship. Conclusion The quantitative analysis of nuclear morphology, DNA content determination of the diagnosis of upper urinary tract transitional cell carcinoma, malignant degree has a certain reference value, DNA content is an important factor affecting the prognosis.