吩噻嗪类抗精神病药和三环抗忧郁剂等向精神药物所致的癫痫样发作已有报告。本例为氯氮平在治疗精神病过程中出现典型的癫痫大发作,其临床表现比较突出,现报告如下。患者男,19岁。1987年10月26日首次住院。精神异常一年余,表现为学习成绩明显下降,发呆,自言自语,无故发笑,幻听,疑被害,怪异动作等。既往无癲痫病史,亦无癫痫家族史。入院诊断精神分裂 Epileptic attacks such as phenothiazine antipsychotics and tricyclic antidepressants have been reported. This case of clozapine in the treatment of mental illness typical epileptic seizures, the more prominent clinical manifestations, are as follows. Male patient, 19 years old. October 26, 1987 first hospitalization. Mental abnormalities more than a year, manifested as a marked decline in academic performance, a daze, talking to himself, for no reason, auditory hallucinations, suspect murdered, weird movements. No past history of epilepsy, nor family history of epilepsy. Admission diagnosis of schizophrenia