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目的探讨阿托伐他汀治疗高脂血症的临床疗效及应用价值。方法选择邢台市成安县人民医院治疗的高脂血症患者272例,用数字表法分为观察组和对照组各136例,对照组给予西医综合治疗,观察组给予阿托伐他汀治疗,记录两组疗效对比。结果观察组治疗后总胆固醇(3.79±0.34)mmol/L,甘油三酯(1.03±0.12)mmol/L,低密度脂蛋白胆固醇(2.79±0.21)mmol/L,上述指标同对照组对比差异具有统计学意义(P<0.05)。观察组治疗后肿瘤坏死因子(62.18±5.65)ng/L,C反应蛋(44.18±4.02)mg/L;对照组治疗后肿瘤坏死因子(98.32±10.05)ng/L,C反应蛋(67.39±7.89)mg/L,组间比较差异有统计学意义(P<0.05)。结论阿托伐他汀治疗高脂血症可以有效减轻炎症反应,改善患者体内血脂浓度。
Objective To investigate the clinical efficacy and clinical value of atorvastatin in the treatment of hyperlipidemia. Methods A total of 272 patients with hyperlipidemia who were treated in Cheng’an County People’s Hospital of Xingtai City were enrolled and divided into observation group (136 cases) and control group (136 cases) by the digital meter method. The control group was treated with western medicine and the observation group was treated with atorvastatin Comparison of two groups of curative effect. Results The total cholesterol (3.79 ± 0.34) mmol / L, triglyceride (1.03 ± 0.12) mmol / L and LDL cholesterol (2.79 ± 0.21) mmol / L after treatment in the observation group were significantly lower than those in the control group Statistical significance (P <0.05). The tumor necrosis factor (62.18 ± 5.65) ng / L and C-reactive protein (44.18 ± 4.02) mg / L in the observation group after treatment were significantly higher than those in the control group (98.32 ± 10.05 ng / L, 67.39 ± 7.89) mg / L, there was significant difference between the two groups (P <0.05). Conclusion Atorvastatin treatment of hyperlipidemia can effectively reduce the inflammatory response and improve the patient’s blood lipids.