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目的 探讨大肠癌术后肝转移手术切除的疗效及影响术后生存率的有关因素,总结改进远期疗效的措施。方法 对87 例大肠癌肝转移病人术后进行长期随访,并对治疗中相关因素进行统计分析,对比研究。结果 全组术后1 、3 、5 年生存率分别为77.0 % 、32.2 % 和24.1 % 。统计分析表明,原发癌病理类型,病灶数目、手术方式及时机选择,术后治疗等是影响术后长期生存的重要因素。结论 早发现早切除,改进治疗中的相关因素,术后密切监测,发现早期复发和转移,争取再切除以及加强术后综合治疗是提高远期疗效的关键
Objective To investigate the curative effect of surgical resection of liver metastasis after colorectal cancer and the related factors affecting the postoperative survival rate, and summarize the measures to improve the long-term efficacy. Methods A long-term follow-up was performed on 87 patients with liver metastases of colorectal cancer, and the related factors in the treatment were statistically analyzed and compared. Results The overall 1-, 3-, and 5-year survival rates of the whole group were 77.0 %, 32.2 % and 24.1 %, respectively. Statistical analysis showed that the primary pathological type of cancer, the number of lesions, the choice of surgical mode and timing, and postoperative treatment are important factors affecting postoperative long-term survival. Conclusion Early detection and early resection, improvement of related factors in the treatment, close monitoring after operation, early recurrence and metastasis, re-excision and postoperative comprehensive treatment are the keys to improve long-term efficacy