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目的:优选肝炎康胶囊的水煎提取制备工艺。方法:采用正交试验L9(34)法,以浸膏率和大黄素含量作为考察指标,优选肝炎康胶囊的最佳水煎提取制备工艺。结果:影响水煎提取工艺的因素次序依次为:提取次数(B)>提取时间(A)>加水倍量(C)。最佳制备工艺条件为A3B3C2,即处方药材加10倍量的水、煎煮提取3次、每次2 h。结论:水煎提取制备工艺合理可行,可用于实际配制。
Objective: To optimize the decoction preparation technology of Heyan Kang capsules. Methods: The orthogonal experiment L9 (34) method was adopted to take the extract rate and the emodin content as the index of investigation, and the best decoction extraction process of Gan Yan Kang Capsule was optimized. Results: The order of influencing decoction extraction process was as follows: extraction times (B)> extraction time (A)> water addition times (C). The best preparation conditions for the A3B3C2, that is, prescription drugs plus 10 times the amount of water, boiling extraction 3 times, each 2 h. Conclusion: The decoction extraction process is reasonable and feasible and can be used in the actual preparation.