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本文对１５０例女性下生殖道尖锐湿疣病人，从临床、病理和实验室方面进行研究。尤其是应用ＰＣＲ方法，对患者的宫颈细胞、局部病灶进行ＨＰＶ—ＤＮＡ的检测，证实女性ＨＰＶ感染好发于性活跃人群，性传播为主要方式，常重叠感染其它ＳＴＤ。病理学对结节菜花型病灶者的诊断可达９７．６％；对簇状粟粒型病灶的诊断仅为５０％，而其余病人用ＰＣＲ检测ＨＰＶ－ＤＮＡ５５％～５９％阳性，证明有ＨＰＶ感染．用ＰＣＲ方法对患者的宫颈脱落细胞和局部病灶同时检测发现，外阴部位的ＨＰＶ感染，几乎同时伴有宫颈和阴道的ＨＰＶ感染。同时还提示ＰＣＲ方法在对ＨＰＶ的检测方面是敏感特异的方法。
In this paper, 150 cases of female genital warts patients, from the clinical, pathological and laboratory aspects of the study. In particular, PCR method was used to detect HPV-DNA in patients with cervical cells and local lesions. It is confirmed that female HPV infection occurs mainly in sexually active people, and sexual transmission is the main way, often overlapping with other STD. Pathological diagnosis of nodular cauliflower-type lesions up to 97.6%; diagnosis of clustered miliary lesions only 50%, while the remaining patients with PCR detection of HPV-DNA 55% -59% positive, that HPV infection . PCR method of cervical exfoliated cells and local lesions in patients with simultaneous detection found that genital HPV infection, accompanied by almost simultaneous cervical and vaginal HPV infection. It is also suggested that the PCR method is a sensitive and specific method in the detection of HPV.