本文报告两例经前正中额部骨瓣颅内外联合入路施行泛眶切除术。术中先切开掀起额骨骨瓣,显露前颅凹底,处理硬脑膜和大脑额叶的受侵部分,然后显露切断鼻根和颌骨额突,最后切断筛骨两侧和后部以及额骨的眶部,包括受肿瘤侵犯的眶内容物一并整块切除。本手术符合肿瘤外科原则、显露清楚,可直视下探查和处理颅底和颅内的受侵组织,对挽救部分较晚期鼻腔、额、筛窦恶性肿瘤患者有一定应用价值,但也有创伤大、毁容严重、危险性较大等缺点。术中应防止损伤上矢状窦,仔细修补硬脑膜,术前术后应重视预防感染。 This article reports two cases of pan-orbital resection combined with intracranial and extracranial approach through the anterior median forearm flap. In the operation, the frontal bone flap was cut open to reveal the anterior surface of the fundus, the affected part of the dural and frontal lobes was treated, and the frontal and maxillary frontal processes were cut off. Finally, both sides and posterior part of the ethmoid bone were cut off, Frontal orbital, including tumor-infiltrated orbital contents together with a total resection. The operation in line with the principle of tumor surgery, revealed clearly, under direct vision to explore and handle the skull base and intracranial invasion of the organization, to save some of the more advanced nasal, frontal, ethmoid malignant tumor patients have some value, but there are trauma , Disfigured, dangerous and other shortcomings. Surgery should prevent injury of the sagittal sinus, carefully repair the dura, preoperative and postoperative should pay attention to the prevention of infection.