蕈样肉芽肿是一种皮肤T细胞淋巴瘤最初侵犯皮肤,后期可侵犯淋巴结及任何内脏器官。本病浸犯骨髓虽较常见,但骨皮质被侵犯实属罕见。此为与其它恶性淋巴瘤不同之点。作者报告一例蕈样肉芽肿患者,经X线拍片证实有广泛的溶骨性破坏。患者男性,47岁,1975年住院,右膝关节多处疼痛及肿胀已3个月。5年前,胸部和两臂发生环状红斑,无自觉症状。73年胸部和两臂发生紫红色斑块和瘤肿,有轻烧灼感。胸部浸润性损害活检证实为蕈样肉芽 Mycosis granuloma is a skin T-cell lymphoma that initially invades the skin and can invade lymph nodes and any internal organs in later stages. Although it is more common to invade the bone marrow of this disease, it is rare that the cortical bone is invaded. This is different from other malignant lymphomas. The authors reported one patient with mycosis granulomatosis confirmed by X-ray radiographs for extensive osteolytic destruction. The patient, male, 47 years old, was hospitalized in 1975 and had suffered multiple pains and swellings in his right knee for 3 months. Five years ago, ring-shaped erythema occurred in the chest and both arms, with no symptoms. In the 73rd year, purple patches and tumors developed on the chest and arms, and there was a slight burning sensation. Chest invasive lesion biopsy confirmed as a granulation granulation