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为了确定免疫复合物在浆液性中耳炎(SOM)发病中是否起重要作用,作者对21例慢性SOM的儿童(月龄30～95月,平均58月)和8例无SOM及其他中耳炎症的耳硬化症成人患者(年龄21～65岁,平均46岁)于安通气管或进行镫骨切除时取中耳粘膜活组织进行免疫组化检查。以OKT_6、Leu_4等多种有关抗体进行间接免疫酶的组化试验。结果SOM感染的粘膜有水肿,密集的炎性细胞浸润。上皮对抗B细
To determine if immune complexes play an important role in the pathogenesis of serous otitis media (SOM), the authors evaluated 21 children with chronic SOM (months 30 to 95 months, mean 58 months) and 8 ears without SOM and other otitis media Sclerosing adult patients (aged 21 to 65 years, mean 46 years) were examined by immunohistochemistry in the middle ear mucosa when anastomosis or tarsal resection was performed. OKT_6, Leu_4 and other antibodies for indirect immunoenzyme histochemistry. Results SOM infected mucosa with edema, dense inflammatory cell infiltration. Epithelium against B thin