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本文报道了根据核浆比,核仁(有或无,模糊不清或明显,数目),核形及细胞大小进行积分分型的方法。按此法,对100例成人急性淋巴细胞白血病(急淋)化疗前的骨髓片进行了形态学分型。结果L_152例,L_240例,L_32例,6例未能定型,在成人急淋中L_1多于L_2。对其中住院的52例进行了临床分析,L_128例中完全缓解(CR)23例,CR率82.2%,L_222例中CR12例,CR率54.5%,经统计学处理L_1与L_2的CR率无明显差异。本文还对积分法分型的意义进行了讨论。
In this paper, we report the method of integrating the nuclear type and cell size according to the ratio of nucleus to plasma, nucleolus (with or without, ambiguous or obvious, number), nuclear shape and cell size. According to this method, 100 cases of adult acute lymphoblastic leukemia (acute lymphoblastic) before the bone marrow chip morphological typing. Results L_152 cases, L_240 cases, L_32 cases, 6 cases failed to stereotypes, in adult acute lymphoblastic L_1 more than L_2. Of the 52 hospitalized patients, 23 cases were completely relieved (CR), the CR rate was 82.2%, the CR rate was 54.5% in L_222 cases, and the CR rate of L_1 and L_2 was not statistically significant difference. This article also discusses the significance of the integral method.