原发性中枢神经系统恶性淋巴瘤（CPML）是一种少见的肿瘤，仅占所有中枢神经系统原发肿瘤的0．3％～1．5％。自60年代以来，发病率有增加趋势，除因近年获得性免疫缺陷疾病病人增多以外，与诊断水平的提高也有关系。由于本病的临床表现复杂，影象学缺乏特异性，以及脑活俭的普 Primary central nervous system malignant lymphoma (CPML) is a rare tumor accounting for 0.3% to 1.5% of all primary tumors of the central nervous system. Since the 1960s, the incidence has been on the rise. Except for the increase of patients with acquired immunodeficiency diseases in recent years, it is also related to the improvement of diagnosis. Due to the complexity of the clinical manifestations of the disease, the lack of specificity of imaging, as well as generalized brain thrifty