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目的 研究模拟失重状态下心功能的变化及套带的防护作用。 方法 12 名受试者,随机分为对照组和套带组,进行了21 天头低位卧床试验。套带组卧床第1~10、18~21 天每天8:30~20:30 四肢戴加压套带,压力维持在(5.3±0.7) kPa,第11~17 天不使用套带;对照组卧床中不用任何对抗措施。在卧床前1 天、卧床第2、3、4、6、9、13、17、21 天和卧床后第3 天,用科飞SF-IV心肺功能检查仪检测SV、CO和STI。 结果 对照组卧床中SV、CO较卧床前明显下降,卧床后第3 天回升,反高于卧床前,对照组卧床中LVET 缩短,PEP、ICT、PEP/LVET、ICT/LVET 延长,卧床后第3天恢复至卧床前水平;套带组卧床中SV、CO 也较卧床前下降,但下降幅度轻于对照组,卧床后第3天回升,幅度也轻于对照组,套带组卧床中LVET 缩短,PEP、ICT、PEP/LVET、ICT/LVET延长,使用套带时比不使用套带时变化更明显,卧床后第3 天恢复至卧床前水平。 结论 21 天头低位卧床使心泵血功能下降,这可能与体液丢失、前负荷减少有关。使用四肢持续加压套带通过对抗体液头向转移,维持有效血容量和前负荷,一定程?
Objective To study the changes of cardiac function and protective effects of cuffs during simulated weightlessness. Methods Twelve subjects were randomly divided into control group and lagging group. The 21-day low bed rest test was performed. Set of stratified bed 1 to 10, 18 to 21 days every day from 8:30 to 20:30 wearing a compression band, the pressure maintained at (5.3 ± 0.7) kPa, the first 11 to 17 days without the use of sets Band; control group bed without any countermeasures. SV, CO, and STI were measured with a Corvette SF-IV cardiopulmonary function test machine 1 day before bedtime, 2, 3, 4, 6, 9, 13, 17, 21 and 3 days after bed rest. Results The SV and CO in the control group decreased significantly compared with those before bed-ridden. The levels of SV and CO in the control group increased significantly on the 3rd day after bed rest, and were significantly higher than those in the control group before bed rest. LVET, ICT, PEP / LVET and ICT / 3 days recovery to the level of bed before bed; bed set group bed SV, CO also decreased compared with the bed, but the decline was lighter than the control group, the first 3 days after bed recovery, amplitude is also lighter than the control group, Shortening, prolongation of PEP, ICT, PEP / LVET, ICT / LVET prolongation, more obvious when using the cuff than without using the cuff, and recover to the level before bedtime on the third day after bed rest. Conclusions The 21-day low bed rest reduces cardiac pump function, which may be related to the loss of body fluid and the decrease of preload. Continued use of pressurized limbs straps through the head to the body fluid transfer to maintain effective blood volume and preload, a certain length?