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体外试验已证实,雷贝拉唑(Rabeprazole)较之其它质子泵抑制剂起效更为迅速,可在5min内使三磷酸腺苷酶接近完全抑制,而奥美拉唑(Omeprazole)和兰索拉唑(Lansoprazole)则需30min。本研究旨在比较雷贝拉唑与雷尼替丁(Ranitidine)治疗活动性十二指肠溃疡的疗效和可耐受性。
In vitro tests have shown that Rabeprazole works more rapidly than other proton pump inhibitors and nearly completely inhibits adenosine triphosphate (ATPase) within 5 min, whereas Omeprazole and Lansoprazole Lansoprazole) takes 30min. This study aimed to compare the efficacy and tolerability of rabeprazole with ranitidine in the treatment of active duodenal ulcer.