存在于淋巴细胞中的多种蛋白酪氨酸激酶（ＰＴＫ）与淋巴细胞表面分子有结构联系，刺激Ｔ淋巴细胞表面特异的抗原受体（ＴＣＲ）可以活化ＰＴＫ。活化的ＰＴＫ又与多种胞内效应分子作用，并通过它们介导级联反应，开启磷酸肌醇途径、激活Ｒａｓ及有丝分裂原活化蛋白激酶（ＭＡＰＫ），进而活化核内因子，最终诱导Ｔ淋巴细胞的活化与增殖。 A variety of protein tyrosine kinases (PTKs) present in lymphocytes are structurally linked to lymphocyte surface molecules that stimulate PTK activation by surface-specific antigen receptors (TCRs) on T lymphocytes. Activated PTK and a variety of intracellular effector molecules, and through their cascade reaction, open the phosphoinositide pathway, activation of Ras and mitogen-activated protein kinase (MAPK), and then activate the nuclear factor, and ultimately induce T lymphocytes Cell activation and proliferation.