在大多数淋巴丝虫病流行区,最适宜的诊断方法是在晚间采血检查微丝蚴。然而,对许多有典型丝虫病症状的病人,尽管采用浓缩等技术也查不出血中的微丝蚴;传统的以粗抗原或组分抗原检测抗体的血清学诊断方法一般不够特异,且不能区分现症感染与过去感染以及虽有接触史却未感染者。近期研究表明,以重组抗原作诊断抗原能克服夜间采血查微丝蚴敏感性低而传统血清学诊断方 In most lymphatic filariasis endemic areas, the most appropriate diagnostic method is to check the microfilaria at night. However, for many patients with typical filariasis symptoms, microfilariae are not detected in blood, even though techniques such as concentration are used. Traditional methods of serodiagnosis for detecting antibodies using either crude or antigenic components are generally not specific and can not Differentiation between infection and infection in the past, as well as contact history but not infected. Recent studies have shown that using recombinant antigens as diagnostic antigens can overcome the low sensitivity of microfilm at night for blood sampling and traditional serological diagnosis