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目的回顾性分析新疆医科大学第一附属医院近7年住院的516例肺血栓栓塞症(pulmonary thromboembolism,PTE)患者的危险因素、临床资料,探讨维、汉两民族PTE患者危险因素构成特点的差异性。方法回顾性分析2004至2010年7年间在新疆医科大学第一附属医院住院的PTE患者的临床资料。统计学处理采用t检验、χ2检验。结果①共纳入资料完整的PTE患者516例,其平均年龄57.5±14.8岁。其中汉族360例(69.8%),平均年龄63.5±15.5岁;维吾尔族156例(30.2%),平均年龄52.8±14.3岁。汉族PTE患者高峰年龄在70岁以上,维吾尔族PTE患者高峰年龄为60～69岁。②维、汉两民族PTE患者临床表现比较差异无统计学意义。③维、汉两民族PTE患者较常见的基础病因和获得性危险因素为年龄≥40岁(87.0%),其次为肥胖(70.5%)、既往栓塞史(60.9%,包括DVT、PTE、脑梗塞、心肌梗死)及高脂血症(38.0%)。维吾尔族PTE人群的主要获得性危险因素中肥胖多见(79.5%),而汉族人群是吸烟(37.8%)。结论年龄≥40岁、肥胖、既往栓塞史及高脂血症可能是PTE患者较常见的获得性危险因素及基础疾病,维吾尔族PTE人群肥胖较多见。本结论尚需进一步开展更多大样本的病例-对照研究验证。
Objective To retrospectively analyze the risk factors and clinical data of 516 patients with pulmonary thromboembolism (PTE) hospitalized in the First Affiliated Hospital of Xinjiang Medical University in recent 7 years and to explore the differences in the characteristics of the risk factors of PTE patients between the two ethnic groups Sex. Methods The clinical data of PTE patients hospitalized in the First Affiliated Hospital of Xinjiang Medical University from 2004 to 2010 were retrospectively analyzed. Statistical analysis using t test, χ2 test. Results ① A total of 516 patients with PTE with complete data were included, with an average age of 57.5 ± 14.8 years. Among them, 360 Han cases (69.8%) had an average age of 63.5 ± 15.5 years and 156 Uyghur cases (30.2%) with an average age of 52.8 ± 14.3 years. Han Chinese PTE peak age of 70 years of age or more, Uygur PTE peak age of 60 to 69 years. There was no significant difference in the clinical manifestations of PTE between the two ethnic groups. ③ The common causes of the underlying and acquired risk factors for PTE in both Chinese and Han nationalities were age ≥40 years (87.0%), followed by obesity (70.5%), previous embolism (60.9%, including DVT, PTE, cerebral infarction , Myocardial infarction) and hyperlipidemia (38.0%). Among the Uighur PTE population, the prevalence of obesity was more common (79.5%) than that of the Han population, while smoking was found in the Han population (37.8%). Conclusion Obesity, history of previous embolism and hyperlipidemia may be the more common risk factors and underlying diseases in PTE patients. The obesity of Uighur PTE population is more common. This conclusion still needs to be further carried out in more large sample of cases - controlled study validation.