论文部分内容阅读
目的:探讨儿童阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)与肥胖的相关性。方法:收集单纯性肥胖儿童120例和体重正常儿童110例作为研究对象,进行统一的体格检查和专科检查,并进行多导睡眠监测记录阻塞性呼吸暂停指数(OAI)、呼吸暂停/低通气指数(AHI)、中枢性呼吸暂停指数(CAI)、最低血氧饱和度(LSa O2)和睡眠效率。结果:肥胖组OSAHS患病率为58.33%显著高于对照组的31.82%,差异有统计学意义(P<0.05);OAI、AHI、CAI均显著高于对照组,而LSa O2、睡眠效率指标显著低于对照组,差异均有统计学意义(均P<0.05);多因素回归分析显示,肥胖、扁桃体增生、腺样体增生是导致OSAHS的独立危险因素,差异有统计学意义(均P<0.05)。结论:肥胖是儿童OSAHS发病的重要影响因素,特别是合并扁桃体肿大或腺样体肿大的患儿应注意预防OSAHS的发生。
Objective: To investigate the relationship between childhood obstructive sleep apnea / hypopnea syndrome (OSAHS) and obesity. Methods: A total of 120 obese children and 110 normal weight children were enrolled in the study. Uniform physical exams and specialist examinations were performed. Obstructive apnea index (OAI), apnea / hypopnea index (AHI), central apnea index (CAI), lowest oxygen saturation (LSa O2) and sleep efficiency. Results: The prevalence of OSAHS in obesity group was 58.33%, which was significantly higher than that in control group (31.82%, P <0.05). The levels of OAI, AHI and CAI in obesity group were significantly higher than those in control group (P <0.05). Multivariate regression analysis showed that obesity, tonsil hyperplasia and adenoid hyperplasia were the independent risk factors of OSAHS (all P <0.05), and the differences were statistically significant <0.05). Conclusion: Obesity is an important factor in the pathogenesis of OSAHS in children. In particular, children with enlarged tonsils or enlarged adenoids should pay attention to the prevention of OSAHS.