MicroRNA-148a suppresses tumor cell proliferation and migration by down-regulating ErbB3 in pancreat

来源 :The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议) | 被引量 : 0次 | 上传用户:applebanana0204
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background & aim ErbB3 is upregulated in pancreatic cancer and has been associated with tumor progression, but little is known about regulatory mechanisms.In this study, we hypothesized that ErbB3 is a target of miR-148a and vertified the hypothesis through molecular methods.
其他文献
Background and aims Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease of unknown etiology and abnormality of hepatobiliary transport might contribute to its pathogenesis.However,
会议
Background The exact cause of ulcerative colitis (UC) remains unknown, the increased secretion of proinflammatory cytokines may be the main pathogenesis of intestinal inflammation.MicroRNA (miRNA) is
会议
Aims To monitor the development of the fecal microbiota of infants during the first year of life, and to investigate the effect of the mode of delivery to the development of gut microbiota.Methods The
会议
Background and aims Standard triple therapy for the eradication of Helicobacter pylori (H.pylori) has been unable to meet the 80% acceptable eradication rate in many parts of the world.Both concomitan
会议
Aim The human apurinic/apyrimidinic endonuclease (APE), an important enzyme in the base excision repair (BER) pathway, was proved to be involved in the process of digestive system cancers.However, the
会议
Objective Human apurinicyapyrimidinic endonuclease (APE-l) is a DNA repair of oxidative base damage key enzyme, APE-1 can repair damaged DNA base which is caused by the reactive oxygen species (ROS).H
会议
Objective To compare the diagnostic rates of intestinal Behcets disease adopted different diagnostic criteria.To evaluate the mucosal healing effect of glucocorticoids used for induction.Methods Conse
会议
Aim Esophageal varix and portal hypertensive gastropathy (PHG) were complications of portal hypertension.Endoscopic esophageal varix eradication has been hypothetized to a trigger of PHGs aggravation.
会议
Objective To detect the expression of Bad, Noxa protein in gastric cancer tissues and its relationship with apoptosis, and to explore its role and significance in gastric cancer pathogenesis.Methods B
会议
Background Annexin A2 (AnxA2) contributes to cancer invasion in solid malignancies such as breast cancer and plays a vital role in inflammatory process and immunoreaction, which have been associated w
会议