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1958～1991年我院收治10例嗅神经母细胞瘤,9例发生于鼻腔,1例发生于颅内。年龄13～53岁。男4例,女6例。根据Kadish分期,A期1例,B期2例,C期6例,1例未分期。所有病人经放射治疗,3例合并手术,1例合并化疗。3例局部复发,2例远处转移,6例病人仍然存活。局部复发是失败的主要原因。预后和临床分期有关,放疗或手术是早期病人的有效治疗手段,晚期应综合治疗。
From 1958 to 1991, 10 cases of olfactory neuroblastoma were treated in our hospital. Nine cases occurred in the nasal cavity and one case occurred in the brain. Age 13 to 53 years old. 4 males and 6 females. According to the Kadish staging, there were 1 case in A stage, 2 cases in B stage, 6 cases in C stage, and 1 case was not staged. All patients were treated with radiation, 3 with surgery, and 1 with chemotherapy. Local recurrence occurred in 3 cases, distant metastasis in 2 cases, and 6 cases remained alive. Local recurrence is the main reason for failure. The prognosis is related to clinical staging. Radiotherapy or surgery is an effective treatment for early patients. Comprehensive treatment should be performed late.