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[目的]探讨复方丹参滴丸对中青年脑卒中患者D-二聚体及同型半胱氨酸(Hcy)的影响。[方法]选择经头颅C T或核磁共振检查证实为脑卒中的青年患者137例,随机分为两组:观察组69例,采用复方丹参滴丸、丁苯酞氯化钠与阿司匹林治疗;对照组68例,仅采用苯酞氯化钠与阿司匹林治疗。比较两组患者急性期与恢复期的血清D-二聚体和 Hcy水平。[结果]经治疗后,两组患者D-二聚体与 Hcy水平呈降低趋势( P <0.05);在急性期和康复期治疗组患者血清D-二聚体与Hcy水平均低于对照组,差异有统计学意义( P<0.05)。[结论]复方丹参滴丸可改善脑卒中患者的血液高凝状态,具有抗血栓、降低D-二聚体及 H cy水平的作用。“,”[Objective]To explore the impact of compound Danshen drip pill(CSDP) on D-dimer and homo-cysteine(Hcy) in young patients with stroke .[Methods]Totally 137 patients with stroke confirmed by cerebral CT or MRI were chosen and divided into two groups .The observation group( n=69) was treated with CSDP , butylphthalide NaCl and aspirin .The control group( n =68) was only treated with butylphthalide NaCl and aspirin .Serum levels of D-dimer and Hcy in patients during acute and rehabilitation period were compared be-tween two groups .[Results]After treatment ,the levels of D-dimer and Hcy in two groups showed a decreasing trend( P < 0 .05) .In acute phase and rehabilitation period ,serum levels of D-dimer and Hcy in treatment group were lower than those in control group ,and there was significant difference( P <0 .05) .[Conclusion]CSDP can improve hypercoagulable state of patients with stroke ,and has the effects such as anti-thrombosis and lowering the levels of D-dimer and Hcy .