本文以HLA抗原作为一种遗传标志,检测了高度近视、高度近视性青光眼两组病人的HLA-A、B抗原,以便从遗传背景上来探索它们之间的关系。我们发现在54例高度近视与44例高度近视性青光眼患者中,汉族人常见的22种HLA-A、B抗原的分布显著不同。这个结果提示,高度近视与高度近视性青光眼虽然都具有高度近视(屈光度≥-6D)和眼底近视性变性等特点,但它们是属于遗传背景不同的两种疾病。 In this paper, HLA antigen as a genetic marker, detection of high myopia and high myopia in patients with two groups of patients with HLA-A and B antigens, in order to explore their genetic background to explore the relationship between them. We found that in 54 patients with high myopia and 44 patients with high myopia glaucoma Han people common 22 HLA-A, B antigen distribution was significantly different. This result suggests that although both high myopia and high myopia glaucoma are characterized by high myopia (refraction ≥-6D) and fundus myopia degeneration, they belong to two different genetic backgrounds.