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目的研究不同的降糖策略及清创时机对糖尿病足溃疡预后的影响。方法将42例糖尿病足溃疡患者随机分为快速降糖组及渐进降糖组,比较组间血糖达标时间、低血糖发生率、足溃疡愈合时间的差异。结果两组不同降糖策略下溃疡愈合时间比较差异无统计学意义。与渐进降糖组比较,快速降糖组血糖达标早、低血糖发生频繁。两组患者清创越早,其溃疡愈合时间越短(P<0.05)。结论糖尿病足溃疡患者住院期间降血糖不应苛求血糖达标,应重视避免低血糖的风险,尽早行清创手术。
Objective To study the effect of different glucose-lowering strategies and the timing of debridement on the prognosis of diabetic foot ulcers. Methods Forty-two patients with diabetic foot ulcer were randomly divided into fast hypoglycemic group and progressive hypoglycemic group, and the differences of blood glucose compliance time, incidence of hypoglycemia, and ulcer healing time were compared between the two groups. Results There was no significant difference in ulcer healing time between the two groups under different hypoglycemic strategies. Compared with progressive hypoglycemic group, fast hypoglycemic group achieved earlier blood glucose, hypoglycemia occurred frequently. The earlier the debridement was, the shorter the ulcer healing time was (P <0.05). Conclusion During the hospitalization of patients with diabetic foot ulcer hypoglycemia should not be demanding blood glucose compliance, should pay attention to avoid the risk of hypoglycemia, debridement surgery as soon as possible.