革兰氏阴性菌释放的脂多糖 (LPS)即内毒素在宿主体内可激活一系列的免疫防御反应 ,反应过度会导致不良的病理生理反应。目前对革兰氏阴性菌性脓毒症的治疗措施有抑制其合成和释放、促进其灭活和排出、中和内毒素、抑制LPS与其受体结合、抑制LPS的瀑布炎症反应、阻抑细胞内信号转导、抗炎治疗等等。但效果尚不十分理想 Gram-negative bacteria release of lipopolysaccharide (LPS) that endotoxin in the host can activate a series of immune defense response, over-reaction will lead to adverse pathophysiological reactions. At present, the treatment of Gram-negative bacterial sepsis inhibits its synthesis and release, promotes its inactivation and excretion, neutralizes endotoxin, inhibits the binding of LPS to its receptor, inhibits the waterfall inflammatory response of LPS, suppresses cells Internal signal transduction, anti-inflammatory treatment and more. But the effect is not very satisfactory