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目的探讨脑卒中后痫性发作的早期预测因素。方法对脑卒中后痫性发作的脑卒中病例的临床资料进行回顾性分析。结果研究期间1031例连续脑卒中病例中79例出现脑卒中后痫性发作,占7.7%。724例缺血性脑卒中、291例颅内出血及16例蛛网膜下腔出血患者中,分别出现脑卒中后痫性发作44例、30例和5例,各占6.1%、10.3%和31.3%。出现脑卒中后痫性发作的患者入院时美国国立卫生研究院脑卒中量表(NIHSS)评分显著高于无痫性发作的患者[(21.8±8.3)分VS(13.9±7.6)分,P<0.01]。多元回归分析提示入院时NIHSS评分是发生脑卒中后痫性发作的独立预测因素(P<0.05)。结论脑卒中后痫性发作常见于脑卒中患者,脑卒中严重程度是脑卒中后痫性发作的预测因素。
Objective To investigate the early predictors of post-stroke epileptic seizures. Methods The clinical data of stroke patients with post-stroke epileptic seizures were analyzed retrospectively. Results Seventy-seven of 1031 consecutive strokes during the study developed post-stroke seizures, accounting for 7.7%. Among 724 ischemic stroke patients, 291 patients with intracranial hemorrhage and 16 patients with subarachnoid hemorrhage, 44 cases were found seizure-induced seizures, 30 cases and 5 cases, accounting for 6.1%, 10.3% and 31.3% respectively, . NIHSS scores were significantly higher in patients with post-stroke seizures than those without seizures [(21.8 ± 8.3) vs 13.9 ± 7.6 (P < 0.01]. Multivariate regression analysis suggested that NIHSS score at admission was an independent predictor of post-stroke epileptic seizures (P <0.05). Conclusions Post-stroke epileptic seizures are common in patients with stroke. The severity of stroke is a predictor of post-stroke seizures.