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观察30例择期胆囊手术病人静脉输入血定安500ml、1000ml和1500ml时对血液流变学的影响。结果:红细胞压积均下降(P<0.05)、红细胞变形指数均升高(P<0.05或P<0.01).而全血比粘度、全血还原粘度、血沉、血沉方程K值和红细胞聚集指数均无明显改变(P>0.05);血浆粘度在大剂量(1500ml)输注时有明显降低(P<0.05)。结论:血定安对血液流变学的影响有利又有弊,尤其是红细胞变形性降低给机体带来的不利影响,应引起临床上的重视。
To observe the hemorheology of 30 patients with elective gallbladder surgery receiving intravenous infusion of 500mg, 1000ml and 1500ml of blood serum. Results: Hematocrit decreased (P <0.05) and erythrocyte deformability index increased (P <0.05 or P <0.01). However, the whole blood viscosity, erythrocyte sedimentation rate, erythrocyte sedimentation rate, erythrocyte sedimentation rate, erythrocyte aggregation index and erythrocyte aggregation index had no significant change (P> 0.05). Plasma viscosity decreased significantly at 1500ml infusion (P < 0.05). Conclusion: Xuedingan has some advantages and disadvantages to the hemorrheology, especially the detrimental effects of the reduced deformability of erythrocytes on the body, which should cause clinical attention.