非甾体解热镇痛剂长期大量应用可引起急性肾功能衰竭、急性间质性肾炎等肾损害,但短期少量使用者出现肾损害少见报道。现报告我科收治的两例病例。 1 临床资料 例1 患者女性,35岁,2000年1月12日因“肉眼血尿原因待查”收住院。患者1999年12月1日始无诱因发热咳嗽,体温波动于38℃～39.4℃,胸透示“肺部感染”,肌注青霉素效果不佳,后改为安灭菌治疗,同时口服速克痛及巴米尔治疗,一周内共用 Non-steroidal antipyretic analgesics long-term large-scale use can cause acute renal failure, acute interstitial nephritis and other kidney damage, but few users of short-term renal damage rarely seen. Now report our department admitted two cases. 1 clinical data example 1 female patient, 35 years old, January 12, 2000 due to “gross hematuria investigation pending” hospital admission. Patients on December 1, 1999 without cause fever cough, body temperature fluctuations at 38 ℃ ~ 39.4 ℃, chest through the “lung infection”, poor muscle injection of penicillin, after the switch to sterilization, while oral Pain and Bamil treatment, shared within a week