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目的：了解卵巢上皮性癌的复发规律，探讨降低复发率的可能措施。方法：回顾性分析１９８５年１月至１９９４年１２月在我院经细胞减灭术后肿瘤残留灶≤２ｃｍ的卵巢上皮癌Ⅰ－Ⅲ期１８９例临床资料，其中Ⅰ期 ８１例、Ⅱ期１９例、Ⅲ期８９例。９７例术后按计划完成铂类药物为主的化疗。结果：１８９例中７０例复发，总的复发率为３７．０％。 １年以内２年以内、３年以内和５年以上的复发患者各占 ４１．４％、６５．７％、７４.３％和 ８．６％。 Ｉ期和 Ⅱ、Ⅲ期的复发率分别为１２.３％和５５．６％（Ｐ＜０.０１）。完成化疗计划者和未完成者的复发率分别为２７．６％和４６.７％（Ｐ＜０．０１）。对年龄、病理类型、手术分期和术后化疗四个因素进行多因素Ｌｏｇｉｓｔｉｃ回归分析表明，手术分期和化疗是影响复发的显著性因素（Ｐ分别＜０．０１和０.０５）。结论：卵巢上皮性癌术后复发大多在３年之内。复发率与手术分期及术后化疗密切相关。早期诊断和术后有计划的化疗可望减少复发，改善预后。
Objective: To understand the recurrence of epithelial ovarian cancer and to explore possible ways to reduce the recurrence rate. Methods: A retrospective analysis of 189 patients with stage Ⅰ-Ⅲ ovarian epithelial carcinoma with residual tumor less than 2cm after cytoreductive surgery in our hospital from January 1985 to December 1994 was performed. Among them, there were 81 cases of stage Ⅰ and Ⅱ Cases, Ⅲ period 89 cases. Ninety-seven patients were scheduled to complete platinum-based chemotherapy. Results: Of 189 cases, 70 cases relapsed, the total recurrence rate was 37.0%. Recurrences within 41%, 65.7%, 74.3% and 8.6% within 1 year, within 2 years, within 3 years and above 5 years respectively. The recurrence rates of stage I, stage II and stage III were 12.3% and 55.6%, respectively (P <0.01). The recurrence rates of those who completed chemotherapy and who did not finish were 27.6% and 46.7%, respectively (P <0.01). Multivariate Logistic regression analysis of age, pathological type, surgical stage and postoperative chemotherapy showed that surgical staging and chemotherapy were the significant factors that affected recurrence (P <0.01 and 0.05, respectively). Conclusion: Postoperative recurrence of ovarian epithelial carcinoma mostly within 3 years. Relapse rate and surgical staging and postoperative chemotherapy are closely related. Early diagnosis and planned chemotherapy are expected to reduce recurrence and improve prognosis.