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本文报道甲硝唑治疗31例破伤风并与28例青霉素常规治疗作为对照组,2组临床资料(包括年龄、性别、病型等)相类似。结果:治愈率治疗组97％(30/31)。对照组89％(25/28)(p>0.05);死亡率治疗组3％(1/31),对照组11％(3/28)(p>0.05)。提示甲硝唑是治疗破伤风的有效和有希望的药物。本文就其作用机理和使用方法等略作探讨。
This article reports the treatment of 31 cases of tetanus with metronidazole and routine treatment with 28 cases of penicillin as a control group, two sets of clinical data (including age, gender, type, etc.) similar. Results: The cure rate in the treatment group was 97% (30/31). The control group was 89% (25/28) (p> 0.05); the mortality rate was 3% (1/31) in the treatment group and 11% (3/28) in the control group (p> 0.05). Tip metronidazole is an effective and promising drug for the treatment of tetanus. This article on its mechanism of action and use of a little discussion.