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目的研究住院危重患者泛耐药鲍氏不动杆菌的定植和感染,加强预防控制,降低其定植率与感染率。方法选择2013年1月-2015年3月泛耐药鲍氏不动杆菌定植与感染的住院危重患者150例为感染组,选择同期未感染泛耐药鲍氏不动杆菌的住院危重患者150例为对照组,比较两组患者的临床资料,分析泛耐药鲍氏不动杆菌的分布及科室来源;采用SPSS20.0软件对数据进行统计分析。结果感染组患者的ICU住院时间(33.82±13.74)d,APACEⅡ评分为(20.13±6.58)分,其中有98例行机械通气占65.33%,死亡51例病死率34.00%,其各方面均明显高于对照组,差异有统计学意义(P<0.05);感染患者共分离出162株泛耐药鲍氏不动杆菌,主要分布于痰液中;150例泛耐药鲍氏不动杆菌感染患者中有44例为院外带入,其余以急诊科为主。结论住院危重患者泛耐药鲍氏不动杆菌的定植和感染与患者的ICU住院时间、APACEⅡ评分、机械通气等有关,应加强管理,降低其定植率和感染率。
Objective To study the colonization and infection of pan-resistant Acinetobacter baumannii in critically ill patients in hospital and to improve the prevention and control and reduce the colonization rate and infection rate. Methods 150 hospitalized critically ill patients with pan-resistant Acinetobacter baumannii infection from January 2013 to March 2015 were selected as the infection group. 150 hospitalized critically ill patients with non-pan-resistant Acinetobacter baumannii As the control group, the clinical data of two groups of patients were compared to analyze the distribution of Pan-resistant Acinetobacter baumannii and the source of the departments; the data were analyzed by SPSS20.0 software. Results The ICU length of hospital stay (33.82 ± 13.74) d and APACE Ⅱ score (20.13 ± 6.58) in infected patients were 98%, of which, mechanical ventilation accounted for 65.33% and death rate was 51%, which was significantly higher in all aspects In the control group, the difference was statistically significant (P <0.05); 162 patients were infected with pan-resistant Acinetobacter baumannii, mainly in sputum; 150 cases of pan-resistant Acinetobacter baumannii infection In 44 cases were brought in from the hospital, the rest mainly to emergency department. Conclusion The colonization and infection of the pan-resistant Acinetobacter baumannii in hospitalized critically ill patients are related to the ICU length of hospital stay, APACEⅡscore, mechanical ventilation and so on. Management and reduction of colonization rate and infection rate should be strengthened.