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目的观察脑血管病意识障碍患者采用纳洛酮与醒脑静联合方案治疗的临床效果。方法利用随机数表将84例脑血管病意识障碍患者分为2组,即常规组与联合组。前者给予常规治疗,后者给予纳洛酮与醒脑静联合疗法。2组均于1个疗程后评估疗效,并观察治疗前后血氨浓度以及神志转醒时间,统计死亡率。结果 2组疗效等级数据比较存在显著差异(P<0.05),且联合组总有效率(95.24%)远高于常规组(73.81%)(P<0.05),2组死亡率比较无显著差异(P>0.05);治疗前联合组与常规组血氨浓度无显著差异(P>0.05),治疗后2组均显著降低(P<0.05),且联合组远低于常规组(P<0.05),联合组神志转醒时间也明显少于常规组(P<0.05)。结论对脑血管病意识障碍病患实施纳洛酮与醒脑静联合治疗能显著改善疗效,还能降低血氨浓度,促进神志转醒。
Objective To observe the clinical effect of combined treatment of naloxone and xingnaojing in patients with cerebrovascular disorder. Methods Using random number table, 84 patients with cerebrovascular disease were divided into two groups: normal group and combined group. The former is given conventional treatment, which is given naloxone and Xingnaojing combination therapy. Two groups were evaluated after a course of treatment efficacy, and observed before and after treatment of serum ammonia concentration and consciousness to wake up time, statistical mortality. Results There was significant difference between the two groups (P <0.05), and the total effective rate (95.24%) in the combined group was significantly higher than that in the conventional group (73.81%) (P <0.05). There was no significant difference in the two groups (P 0. 05). There was no significant difference between the two groups (P 0. 05), and the combined group was much lower than the conventional group (P 0. 05) , The combined group conscious mind wake time was significantly less than the conventional group (P <0.05). Conclusion Naloxone combined with xingnaojing can significantly improve the curative effect of patients with cerebrovascular disease and disturbance of consciousness, but also reduce the concentration of serum ammonia and promote conscious awakening.