论文部分内容阅读
目的评估点刺试验与血清特异性IgE检测在蒿属花粉症中的诊断价值。方法选取夏秋季变应性鼻炎、变应性哮喘及变应性结膜炎患者98例,行蒿属花粉等20种常规吸入物过敏原皮肤点刺试验及UniCAP100系统检测蒿属血清特异性IgE。根据典型的病史、症状、点刺试验、血清学检测结果确立综合诊断标准,以此评价点刺试验及血清特异性IgE的诊断价值,并分析两者之间的相关性。结果 98例患者中,皮肤点刺试验蒿属阳性者为83例,血清特异性IgE检测结果≥1级者75例,且二者等级呈正相关。以综合诊断为确诊标准时,点刺试验敏感度为95.0%,高于血清学特异性IgE检测(88.8%)。结论点刺试验对花粉症的诊断价值大于血清学IgE检测,可以有效、安全地诊断蒿属花粉过敏症。
Objective To assess the diagnostic value of prick test and serum-specific IgE assay in artemisia. Methods Ninety-eight patients with allergic rhinitis, allergic asthma and allergic conjunctivitis in summer and autumn were selected. 20 conventional inhalation allergens skin prick tests including artemisia pollen and UniCAP100 system were used to detect serum-specific IgE. According to the typical history, symptoms, prick tests, serological test results to establish a comprehensive diagnostic criteria to evaluate prick test and serum-specific IgE diagnostic value, and analyze the correlation between the two. Results Among the 98 patients, 83 were tested positive for artemisia by skin prick test and 75 were ≥1 for serum specific IgE test, and their grades were positively correlated. The sensitivity of prick test was 95.0%, which was higher than that of serological specificity IgE assay (88.8%). Conclusion The diagnostic value of prick test to hay fever is greater than that of serological IgE, which can effectively and safely diagnose pollen allergy of Artemisia.